FASORACETAM

Fasoracetam is one of the best general cognitive enhancers in the world and certainly one of the most effective nootropics for treating ADHD symptoms such as lack of focus and mental fatigue. Fasoracetam is a synthetic compound from the racetam group, i.e. substances with nootropic effects. Its supplementation results in increased motivation, better memory and improved cognitive abilities, and is also beneficial for mood stabilization. It has been shown to be able to alleviate attacks of fear and anxiety.

Fasoracetam works by simultaneously increasing the inhibitory neurotransmitter GABA and inhibiting excessive glutamate production to produce the excitatory neurotransmitter. There is no tremors, a smooth feeling of peace, relaxation and improved mood.

One of the most important effects of fasoracetam is the modulation of metabotropic glutamate receptors (mGluR). These receptors are strongly involved in neuroplasticity and are important in protection against neurodegenerative diseases. Additionally, fasoracetam is an agonist of glutamate receptors, which explains its beneficial effect on reducing anxiety disorders.

Fasoracetam is also the only member of the racetam family that enhances the synthesis of adenosine monophosphate (cAMP). cAMP is a secondary messenger involved in most biological changes occurring in the body. This compound also regulates the opening of HCN channels located in the hippocampus. These channels are nucleotide gated, so an increased level of cAMP improves their functioning. As a result, fasoracetam is successfully used to support cognitive functions and prevent memory loss.

Moreover, fasoracetam, because it modulates the activity of cholinergic receptors, significantly increases the concentration of acetylcholine and thus improves memory and cognitive functions. It also interacts with GABA-B receptors - it has the ability to up-regulate them, while increasing the concentration of GABA in the central nervous system. Therefore, by eliminating unnecessary and redundant information, it allows you to better cope with stress and maintain inner peace despite the surrounding chaos.

Like other racetams, fasoracetam has the ability to improve memory. This positive effect is due to the influence of this substance on several aspects related to the process of remembering, including appropriate cataloging of acquired information, its conversion into long-term memory, and facilitating its retrieval at a later time. Animal studies also showed that fasoracetam is successfully used in the treatment of amnesia induced by the administration of scopolamine (a derivative of hyoscyamine, a toxic tropane alkaloid). As a result, this racetam has also been used in the treatment of dementia in people diagnosed with Alzheimer's disease.

The beneficial effect on the creation of a memory trace, and the more effective process of absorbing information, makes fasoracetam a substance eagerly used by students during periods of increased intellectual effort (e.g. during a session).

This effect is mainly responsible for increasing the activity of the cholinergic system. Research results suggest that fasoracetam increases choline uptake in the cerebral cortex and hippocampus, and thus stimulates the synthesis of acetylcholine - one of the most important excitatory neurotransmitters.

It has been proven that supplementation with fasoracetam has a positive effect on increasing the level of motivation. A study conducted on rodents showed that giving them this racetam allowed them to swim a certain distance underwater, while rats that were not given fasoracetam drowned and died. These animals were then subjected to brain imaging and the results obtained proved that fasoracetam increases the density of GABA-B receptors, thus increasing the level of motivation and allowing one to better cope with stressful conditions.

Dosage

20-40mg – once to twice a day